NICER Study: Resting Outcomes in Non-MI

The Calm Before the Evil 😎

Hopefully this great new release from Blume finds you well rested and ready for the dastardly geek-en-shpeal about to befall us all on this night.

I will try and restrain the evil side in me as much as I can, but you know... science is a cruel beast sometimes 😉

The Subgroups Explained

So before we begin, I thought it might be useful to remind ourselves of the different subgroups I used in these studies, what they mean and why they're used. Because otherwise, the level of evil I am about to unleash would be too much even for my own level of disturbance standards 🙂

The Retrospective Review Study

To the left is a link to both a detailed, geek-speak version of the results and a more mellow version of the summaries mixed in. I thought it might be better to link to that here, rather than repeating it in full. Because again, evil but a little bit sane.

Sort of. Maybe. No? I see... don't bother, too late 😭

Unleashing the Evils of Geek

Here's what the results showed for the first time (because data like this had never been reviewed quite the same way before):

  1. There were statistically significant (i.e. the analysis of numbers only, using statistics) average reductions in HR in males and females, but they were pretty slight in terms of real life... as in real values, that we would call 'clinically significant' changes or outcomes for patients;

2. When you compared SB subgroups, blood pressure was raised after the program in SB1 patients (i.e. those with low blood pressure at the beginning) and lowered in SB3 patients (i.e. those with high blood pressure at the beginning);

3. Probably the most interesting thing to come out of all the pretty geeky stuff... when you compare patients after grouping them into SB groups, and then dividing each of those groups AGAIN into smaller MC groups, the picture changes again, and we see some more... 'ranking' sort of... called stratification, of the changes, which we're seeing here for the first time in like... ever!

-2

Overview

So in this study, after all the evil geekiness, we can see some important (albeit painful to witness and even more painful to actually develop) results that show us the effects of the type of exercise program that was used in the cardiac rehabilitation ward of the hospital where I did my research, before the NICER intervention that I tested. The key messages here: this exercise program CORRECTS blood pressure, rather than a blanket decrease for everyone, and the combination of subgroups shows us some new and interesting trends.

Mwah-ha-ha-ha-ha

[pinky finger to corner of smirk]

Stay awesome you cruel and evil geniuses,

EMH